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Updated: May 17, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Sonographic findings in three cases of carcinoma showing thymus-like differentiation
Yayoi Yamamoto1, Keiko Yamada, Noriko Motoi
1Cancer Institute Hospital, Diagnostic Imaging, 3-8-31 Ariake, Koto-ward, Tokyo 135-8550; Japanese Foundation for Cancer Research, Pathology, 3-8-31 Ariake, Koto-ward, Tokyo 135-8550.
Abstract:
Carcinoma showing thymus-like differentiation (CASTLE) is a rare tumor of the thyroid gland or soft tissues of the head and neck. To our knowledge, there have been only a few reports concerning imaging findings of CASTLE. We report herein the sonographic appearances of three cases of CASTLE. Two tumors were located at the lower part of the thyroid and one had spread throughout the thyroid. Sonograms showed heterogeneously solid tumors without cystic components or calcification. The central part of the tumor was slightly hyperechoic compared with the peripheral part of the tumor. Histologically, the tumors were composed of a mixture of fibrous stroma and epithelial nests.

