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Quail Chorioallantoic Membrane - A Tool for Photodynamic Diagnosis and Therapy
07:43

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Published on: April 28, 2022

Multifocal photodynamic therapy for diffuse choroidal hemangioma.

Marcus Ang1, Shu-Yen Lee

  • 1Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.

Clinical Ophthalmology (Auckland, N.Z.)
|October 12, 2012
PubMed
Summary
This summary is machine-generated.

Diffuse choroidal hemangiomas in Asian patients, like this case of Sturge-Weber syndrome, often need multiple photodynamic therapy (PDT) sessions for effective treatment and resolution of subretinal fluid.

Keywords:
Sturge-Weber syndromechoroidal hemangiomaoptical coherence tomography

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Area of Science:

  • Ophthalmology
  • Vascular Oncology

Background:

  • Choroidal hemangiomas are rare benign vascular tumors.
  • Diffuse forms, particularly in Asian patients, present unique treatment challenges.

Observation:

  • A 7-year-old boy with Sturge-Weber syndrome presented with a diffuse choroidal hemangioma.
  • Five photodynamic therapy (PDT) sessions were administered over one year.

Findings:

  • Initial PDT sessions were insufficient for complete tumor destruction.
  • Recurrent subretinal fluid, not tumor size, guided the decision for repeat treatments.
  • Final visual acuity was 20/100 with resolved subretinal fluid and hemangioma.

Implications:

  • Larger, dilated vessels in choroidal hemangiomas may reduce PDT efficacy in Asian patients.
  • Multiple PDT sessions may be necessary for optimal outcomes in this demographic.
  • This case highlights the need for tailored PDT protocols for diffuse choroidal hemangiomas.