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Published on: August 25, 2022
Neonatal heparin overdose-a multidisciplinary team approach to medication error prevention
Jason Arimura1, Robert L Poole, Michael Jeng
1Pharmacy Department, Lucile Packard Children's Hospital at Stanford.
Insights
System failures can cause dangerous medication errors, as seen when nine neonates received fatal heparin doses. This review examines heparin overdose causes and prevention strategies to improve patient safety.
Area of Science:
- Medical Safety
- Pharmacology
- Neonatal Care
Background:
- Medication errors pose significant risks, particularly in hospital settings.
- System failures have been identified as a critical factor in adverse drug events.
- Neonates are a vulnerable population susceptible to severe complications from medication errors.
Purpose of the Study:
- To review the contributing factors leading to heparin medication errors in neonates.
- To identify and analyze the causes of potentially fatal heparin overdoses.
- To propose strategies for minimizing the risk of heparin overdose in clinical practice.
Main Methods:
- Literature review of reported heparin medication errors.
- Analysis of system failures and contributing factors.
- Case study review of nine neonate incidents (2006-2007).
Main Results:
- Identified system failures as a primary cause of heparin overdose.
- Highlighted specific contributing factors, such as dosage miscalculation and administration errors.
- Documented nine instances of neonates receiving potentially fatal heparin doses.
Conclusions:
- Systemic improvements are crucial to prevent heparin medication errors.
- Enhanced protocols and vigilance are necessary to safeguard neonates from heparin overdose.
- Addressing identified risk factors can significantly improve patient safety and reduce adverse events.
Abstract:
Despite the efforts of many hospitals, system failures can result in medication errors that may be life threatening. During 2006 and 2007, nine neonates received potentially fatal doses of heparin. This paper will review contributing factors to the heparin medication errors and ways to minimize the risk of heparin overdose.
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