Clevidipine controls intraoperative blood pressure in an adolescent with renal failure
Joseph D Tobias1, Joy Allee, Venkataraman Ramachandran
1Department of Anesthesiology, University of Missouri, Columbia, Missouri ; Department of Pediatrics, University of Missouri, Columbia, Missouri.
Abstract:
In pediatric-aged patients, various factors may result in perioperative hypertension including renal failure or insufficiency, volume overload, or other factors that activate the sympathetic nervous system including pain and agitation. Perioperative blood pressure control may be even more difficult to achieve and maintain in patients with pre-existing hypertension. We present a 16-year-old adolescent with renal failure and hypertension who presented for anesthetic care during placement of a peritoneal dialysis catheter. Perioperative blood pressure control was achieved with the administration of clevidipine, an ultra-short acting calcium channel antagonist of the dihydropyridine class. Its role in the perioperative control of blood pressure is discussed.
Related Concept Videos
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant
Drug Dosing in Renal Diseases: Measurement of Serum Creatinine Concentration and Clearance
Antihypertensive Drugs: Direct Renin Inhibitors
Pharmacokinetics in Pediatric Patients: Drug Excretion
Antihypertensive Drugs: Potassium-Sparing Diuretics
Continuous Renal Replacement Therapy
