Related Experiment Video
Updated: May 17, 2026

Swimming Exercise Protocol and Care Methods for Pregnant Rats
Published on: April 5, 2024
Impact of maternal physical activity and infant feeding practices on infant weight gain and adiposity
Lisa Chu1, Ravi Retnakaran, Bernard Zinman
1The Hospital for Sick Children, Department of Pediatrics, University of Toronto, 555 University Avenue, Toronto, ON, Canada M5G 1X8.
Insights
Maternal physical activity and exclusive breastfeeding significantly impact infant weight gain and adiposity by age one. Higher maternal activity and longer breastfeeding duration are linked to reduced offspring weight.
Area of Science:
- Pediatrics
- Public Health
- Maternal-Fetal Medicine
Background:
- Intrauterine exposures influence offspring obesity risk.
- Limited research explores maternal and infant lifestyle factors in this context.
Purpose of the Study:
- To investigate the impact of maternal physical activity, infant feeding practices, and screen time on offspring weight gain and adiposity.
- To identify key modifiable factors influencing early-life weight trajectories.
Main Methods:
- Prospective cohort study of 246 mothers.
- Assessment of maternal glucose tolerance and insulin sensitivity during pregnancy.
- Collection of anthropometric data and questionnaires on lifestyle factors (physical activity, infant feeding, screen time).
- Multiple linear regression analysis to determine associations with infant weight outcomes at 1 year.
Main Results:
- Maternal pregravid vigorous/sport index negatively predicted infant weight gain and weight-for-length z-score.
- Exclusive breastfeeding duration showed a negative association with infant weight gain and weight-for-length z-score.
- Each unit increase in maternal activity index reduced infant weight gain by 218.6g and z-score by 0.20.
- Each month of exclusive breastfeeding reduced infant weight gain by 116.4g and z-score by 0.08.
Conclusions:
- Maternal physical activity levels before and during pregnancy are associated with offspring adiposity at 1 year.
- Duration of exclusive breastfeeding is a significant protective factor against early-onset infant weight gain and adiposity.
- These modifiable maternal and infant factors play a crucial role in early-life obesity prevention.
Abstract:
Increasing evidence supports the contribution of intrauterine environmental exposures on obesity risk in offspring. Few studies have included maternal and infant lifestyle factors. Our objective was to study the impact of maternal physical activity, infant feeding, and screen time on offspring weight gain and adiposity. In a prospective cohort study, 246 mothers underwent testing during pregnancy to assess glucose tolerance status and insulin sensitivity. Anthropometry and questionnaires on physical activity, infant feeding, and screen time were completed. Multiple-linear regression was performed to examine the impact of maternal and infant factors on infant weight gain and weight-for-length z-score at 1 year. Infant weight outcomes were negatively predicted by maternal pregravid vigorous/sport index and exclusive breastfeeding duration. After adjustment, each unit increase in maternal pregravid vigorous/sport index decreased infant weight gain by 218.6 g (t = 2.44, P = 0.016) and weight-for-length z-score by 0.20 (t = 2.17, P = 0.031). Each month of exclusive breastfeeding reduced infant weight gain by 116.4 g (t = 3.97, P < 0.001) and weight-for-length z-score by 0.08 (t = 2.59, P = 0.01). Maternal pregravid physical activity and exclusive breastfeeding duration are associated with weight gain and adiposity as early as 1 year of age.
More Related Videos
05:04A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
03:19Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Related Concept Videos
Obesity
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Development of the Oral Microbiota
Environmental Influences on Intelligence
Drug Dosing: Obese Patients