Evidence based medicine in pediatric practice: brief review

Related Experiment Videos

Hamid-Reza Kianifar1, Javad Akhondian, Mehri Najafi-Sani

  • 1Department of Pediatrics, Mashhad University of Medical Sciences, Mashhad, IR Iran.

Iranian Journal of Pediatrics
|October 12, 2012
PubMed

Insights

Evidence-Based Medicine (EBM) offers a better approach to pediatric care. This review explains EBM and its pediatric applications to help doctors integrate it into daily practice.

Area of Science:

  • Pediatric Medicine
  • Clinical Practice Guidelines

Background:

  • Evidence-Based Medicine (EBM) is increasingly adopted in medical fields.
  • EBM principles are underrepresented in pediatric literature and practice.

Purpose of the Study:

  • To review the Evidence-Based Medicine approach.
  • To detail EBM applications specifically for pediatrics.
  • To facilitate EBM integration into pediatricians' daily workflows.

Main Methods:

  • Literature review of Evidence-Based Medicine.
  • Analysis of EBM principles and their relevance to pediatrics.

Main Results:

  • EBM provides a framework for evidence-informed medical decision-making.
  • Specific examples of EBM application in pediatrics are discussed.

Conclusions:

  • Integrating EBM into pediatrics is crucial for optimal patient care.
  • This review serves as a guide for pediatricians to adopt EBM practices effectively.

Keywords:
ChildCritical appraisalEvidence-based medicinePediatrics

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Methods of Documentation V: CBE01:23

Methods of Documentation V: CBE

Charting by Exception, or CBE, is a method of documentation used in healthcare, particularly in nursing, that focuses on documenting only significant or abnormal findings rather than recording every detail. This approach aims to streamline the documentation process, improve efficiency, and ensure that healthcare providers can quickly identify deviations from normalcy in patient assessments.
In CBE, healthcare professionals establish predefined standards of practice that define what constitutes...