Nephrotic Syndrome Following H1N1 Influenza in a 3-Year-Old Boy

Pietro Ferrara1, Antonio Gatto, Ottavio Vitelli

  • 1Department of Pediatric Sciences, A. Gemelli University Hospital, Rome, Italy ; Campus Bio-Medico University, Rome, Italy.

Insights

Influenza A/H1N1 can cause kidney problems, like nephrotic syndrome, even in children. Early antiviral treatment with oseltamivir aided recovery in a pediatric case.

Area of Science:

  • Pediatric Nephrology
  • Infectious Diseases

Background:

  • The 2009 influenza A/H1N1 pandemic caused widespread illness.
  • Influenza complications typically affect the respiratory system, particularly in vulnerable age groups.

Observation:

  • A 3-year-old boy presented with nephrotic syndrome following an upper respiratory infection.
  • The patient tested positive for influenza A/H1N1.

Findings:

  • Treatment with oseltamivir, prednisone, furosemide, and albumin resulted in progressive clinical and laboratory improvement.
  • Renal function normalized within a 2-month follow-up period.

Implications:

  • This case highlights the potential for renal complications following influenza A/H1N1 infection in children.
  • Consideration of renal involvement is crucial in pediatric patients with influenza, even without typical risk factors.
Abstract

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