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Published on: February 14, 2011
Haemophagocytic syndrome associated with mucormycosis infection
V Arena1, F De-Giorgio, I Pennacchia
1Pathologic Anatomy Unit, Catholic University, Rome, Italy. vincenzo.arena@rm.unicatt.it
Abstract:
Several clinical forms of mucormycosis are recognized. The tendency of mucoraceous zygomycetes to invade the blood vessels often produces a disseminated infection. A case of disseminate mucormycosis complicated by a haemophagocytic syndrome (HS) in a 32-year-old Caucasian male is reported in this article. Few cases of infection-associated HS (IAHS), involving infections caused by fungi, have been reported. In all the recorded cases, the fungal infection coexists with malignant lymphoma, immunodeficiency and a long-term steroid therapy for renal transplant or Crohn's disease. This is the second described case of the HS due to mucormycosis.
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