Related Experiment Video
Updated: May 17, 2026

10:52
Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques
Published on: June 1, 2016
Direct observation of internalization and ROS generation of amyloid β-peptide in neuronal cells at subcellular
Yong Jiao1, Yi Zhang, Yibin Wei
1Institute of Molecular Science, Key Laboratory of Chemical Biology and Molecular Engineering of the Ministry of Education, Shanxi University, Taiyuan 030006, P. R. China.
Chembiochem : a European Journal of Chemical Biology
|October 13, 2012
Abstract:
Seeing in many colors: Confocal images acquired using fluorescently labeled amyloid β-peptide revealed its efficient internalization by endocytosis into endosomes/lysosomes of human neuronal cells with a small portion reaching mitochondria, inducing marked cellular and mitochondrial reactive oxygen species production.

