Latin American algorithm for treatment of relapsing-remitting multiple sclerosis using disease-modifying agents

Alessandro Finkelsztejn1, Alberto Alain Gabbai, Yara Dadalti Fragoso

  • 1Department of Neurology, Hospital de Clínicas de Porto Alegre, Porto Alegre RS, Brazil. alessandro.finkels@gmail.com

Insights

Latin American experts developed new multiple sclerosis (MS) treatment guidelines addressing regional challenges. These evidence-based recommendations improve access to disease-modifying therapies for MS patients in Latin America.

Area of Science:

  • Neurology
  • Clinical Pharmacology

Background:

  • Relapsing-remitting multiple sclerosis (RRMS) affects approximately 50,000 individuals in Latin America.
  • Existing European and North American treatment algorithms do not adequately address regional healthcare access and treatment challenges.

Framework:

  • The Latin American Multiple Sclerosis Forum, an independent expert group, convened to address these disparities.
  • The Forum evaluated scientific evidence on the efficacy and safety of disease-modifying treatments (DMTs).

Implementation:

  • Analysis included treatment access and pharmacovigilance programs across eight represented Latin American countries.
  • A tailored set of evidence-based guidelines specifically for Latin America was developed.

Implications:

  • This initiative provides region-specific recommendations for multiple sclerosis management.
  • The guidelines aim to enhance patient access to appropriate and effective DMTs.
  • Future perspectives for multiple sclerosis treatment in Latin America were also discussed.
Abstract

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