Latin American algorithm for treatment of relapsing-remitting multiple sclerosis using disease-modifying agents

Area of Science:

• Neurology
• Clinical Pharmacology

Background:

• Relapsing-remitting multiple sclerosis (RRMS) affects approximately 50,000 individuals in Latin America.
• Existing European and North American treatment algorithms do not adequately address regional healthcare access and treatment challenges.

Framework:

• The Latin American Multiple Sclerosis Forum, an independent expert group, convened to address these disparities.
• The Forum evaluated scientific evidence on the efficacy and safety of disease-modifying treatments (DMTs).

Implementation:

• Analysis included treatment access and pharmacovigilance programs across eight represented Latin American countries.
• A tailored set of evidence-based guidelines specifically for Latin America was developed.

Implications:

• This initiative provides region-specific recommendations for multiple sclerosis management.
• The guidelines aim to enhance patient access to appropriate and effective DMTs.
• Future perspectives for multiple sclerosis treatment in Latin America were also discussed.