Related Experiment Video
Updated: May 17, 2026
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Diffusion-weighted MRI and PSA correlations in patients with prostate cancer treated with radiation and hormonal
Yuko Iraha1, Sadayuki Murayama, Ayano Kamiya
1Department of Radiology, Graduate School of Medical science, University of the Ryukyus, 207 Uehara, Nishihara-cho, Okinawa 903-0215, Japan. irayu@med.u-ryukyu.ac.jp
Aim:
To investigate the correlation between signal intensity (SI) on diffusion-weighted imaging (DWI) and the levels of prostate-specific antigen (PSA) in patients with prostate cancer treated with radiation and hormonal therapy.
Patients And Methods:
Forty-four patients with prostate cancer treated with hormonal therapy and radiation therapy were evaluated. Areas with high SI on DWI were detected and the apparent diffusion co-efficient (ADC) values were measured. The ADC values and PSA levels were compared between patients with high-DWI SI and patients with a normal DWI signal.
Results:
Fourteen patients had high SI on DWI. The mean ADC value in these cancerous lesions was lower than in non-cancerous tissues. The mean PSA level in patients with high-DWI SI was significantly higher than in patients with a normal signal.
Conclusion:
The present results suggest that SI on DWI appears to correlate with PSA levels in patients with prostate cancer treated with radiation and hormonal therapy.
