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Morphologic changes in acute central serous chorioretinopathy using spectral domain optical coherence tomography
Hyung Chan Kim1, Won Bin Cho, Hyewon Chung
1Department of Ophthalmology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. eyekim@kuh.ac.kr
Korean Journal of Ophthalmology : KJO
|October 13, 2012
Summary
Spectral domain optical coherence tomography (SD-OCT) reveals diverse morphologic changes in acute central serous chorioretinopathy (CSC). These findings enhance understanding of CSC pathophysiology, including RPE abnormalities and subretinal fluid resolution.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Diseases
Background:
- Central serous chorioretinopathy (CSC) is a condition affecting vision.
- Morphologic changes in acute CSC are not fully understood.
Purpose of the Study:
- To investigate morphologic changes in acute central serous chorioretinopathy (CSC).
- Utilized spectral domain optical coherence tomography (SD-OCT) and confocal scanning laser ophthalmoscopy.
Main Methods:
- Retrospective study of 63 eyes with unilateral acute CSC.
- Simultaneous SD-OCT and fluorescein angiography performed using Spectralis HRA+OCT.
Main Results:
- External limiting membrane visible on SD-OCT; photoreceptor IS/OS junction visualized after serous retinal detachment resolution in 81%.
- Retinal pigment epithelium (RPE) bumps (68.1%) and pigment epithelial detachments (PED) (31.9%) observed at leakage sites.
- Subretinal fibrinous exudate (20.3%) and posterior retinal layer sagging (13.0%) noted; fellow eyes showed RPE changes (54.5%).
Conclusions:
- SD-OCT identifies various morphologic changes in acute CSC.
- Findings contribute to a better understanding of CSC pathophysiology.
