Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dual-imaging nanoparticles based on surface-modified magnetic nanoparticles and biodegradable photoluminescent polymers.

Frontiers in bioengineering and biotechnology·2025

Same author

Synthesis and characterization of a novel pH-responsive drug-releasing nanocomposite hydrogel for skin cancer therapy and wound healing.

Journal of materials chemistry. B·2021

Same author

Pulsed focused ultrasound lowers interstitial fluid pressure and increases nanoparticle delivery and penetration in head and neck squamous cell carcinoma xenograft tumors.

Physics in medicine and biology·2020

Same author

Decreased nonspecific adhesivity, receptor-targeted therapeutic nanoparticles for primary and metastatic breast cancer.

Science advances·2020

Same author

Thermo-responsive Fluorescent Nanoparticles for Multimodal Imaging and Treatment of Cancers.

Nanotheranostics·2020

Same author

Engineering of L-Plastin Peptide-Loaded Biodegradable Nanoparticles for Sustained Delivery and Suppression of Osteoclast Function In Vitro.

International journal of cell biology·2019

Search research articles

Related Experiment Video

Updated: May 17, 2026

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Published on: June 18, 2013

Dual-imaging enabled cancer-targeting nanoparticles.

Aniket S Wadajkar¹, Tejaswi Kadapure, Yi Zhang

¹Department of Bioengineering, The University of Texas at Arlington, 500 UTA Boulevard, Arlington, TX 76019, USA.

Advanced Healthcare Materials

|October 13, 2012

Summary

New biodegradable dual-imaging cancer-targeting nanoparticles (DICT-NPs) offer improved MRI and optical imaging without photobleaching or cytotoxicity. These nanoparticles enable magnetic targeting for potential cancer cell selectivity.

More Related Videos

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

Related Experiment Videos

Last Updated: May 17, 2026

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Analysis of Targeted Viral Protein Nanoparticles Delivered to HER2+ Tumors

Published on: June 18, 2013

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

Area of Science:

Biomedical Engineering
Nanotechnology
Materials Science

Background:

Current dual-imaging nanoparticles often use photobleaching organic dyes or cytotoxic quantum dots.
There is a need for safer, more stable nanoparticles for cancer imaging and targeting.

Purpose of the Study:

To develop novel biodegradable dual-imaging cancer-targeting nanoparticles (DICT-NPs).
To address limitations of existing dual-imaging agents regarding stability and toxicity.

Main Methods:

Synthesized biodegradable photoluminescent polymers.
Incorporated superparamagnetic iron oxide nanoparticles (SPIONs) into the polymer matrix.
Characterized the dual-imaging and targeting capabilities of the developed DICT-NPs.

Main Results:

Successfully developed DICT-NPs integrating magnetic resonance imaging (MRI) and optical imaging functionalities.
DICT-NPs demonstrated magnetic targeting capabilities.
The biodegradable nature and lack of cytotoxic components address safety concerns.

Conclusions:

The developed DICT-NPs represent a promising advancement in cancer theranostics.
These nanoparticles offer a safer and more effective alternative for dual-modal cancer imaging and targeted delivery.