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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
[A man with thyroid abnormalities: ectopic parathyroid adenoma and multifocal thyroid carcinoma]
H W S Kwee1, Vikash Marapin, Joost M A Verkeyn
1St. Jans Gasthuis, Weert, Afd. Pathologie, the Netherlands. w.kwee20@gmail.com
Nederlands Tijdschrift Voor Geneeskunde
|October 16, 2012
Summary
Simultaneous parathyroid adenoma and thyroid cancer are rare. This case highlights the need for thorough thyroid evaluation in primary hyperparathyroidism patients to detect concurrent conditions.
Area of Science:
- Endocrinology
- Surgical Oncology
- Pathology
Background:
- Thyroid abnormalities are common in primary hyperparathyroidism, affecting up to 70% of patients.
- The co-occurrence of parathyroid adenoma and non-medullary thyroid carcinoma is an infrequent clinical presentation.
Observation:
- A 39-year-old male with hypertension and nephrolithiasis presented with suspected parathyroid adenoma based on lab results and thyroid scintigraphy.
- Initial frozen section analysis revealed papillary thyroid carcinoma metastases, with subsequent biopsy confirming thyroid carcinoma.
- Intrathyroidal parathyroid adenoma and multifocal papillary thyroid carcinoma were discovered upon thyroidectomy and histopathological examination.
Findings:
- Histopathological examination confirmed the simultaneous presence of an intrathyroidal parathyroid adenoma and multifocal papillary thyroid carcinoma.
- Post-thyroidectomy, parathyroid hormone and calcium levels decreased, supporting the diagnosis of both conditions.
Implications:
- This case underscores the critical importance of comprehensive thyroid gland evaluation in patients diagnosed with primary hyperparathyroidism.
- Thorough assessment is essential to identify or rule out the rare but significant co-presentation of parathyroid adenoma and thyroid carcinoma.
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