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Common features of anaphylaxis in children

M Serbes1, D Can, F Atlihan

  • 1Dr Behcet Uz Chidren Hospital, Department of Pediatric Allergy, Izmir, Turkey.

Allergologia Et Immunopathologia
|October 16, 2012
PubMed

Insights

Childhood anaphylaxis is often linked to allergies. Venom immunotherapy (VIT) and food are common triggers, with respiratory symptoms being most frequent. Further research is needed on VIT-induced anaphylaxis.

Area of Science:

  • Pediatric Allergy and Immunology
  • Clinical Immunology
  • Emergency Medicine

Background:

  • Anaphylaxis in children presents unique challenges.
  • Understanding triggers and clinical manifestations is crucial for effective management.
  • Concomitant allergic diseases are common in pediatric anaphylaxis.

Purpose of the Study:

  • To characterize anaphylaxis in a pediatric cohort.
  • To identify common triggers, symptoms, and outcomes.
  • To evaluate the role of specific triggers like venom immunotherapy.

Main Methods:

  • Retrospective analysis of 44 pediatric anaphylaxis cases over 10 years.
  • Data collected on patient demographics, allergic history, triggers, symptoms, and treatment.
  • Statistical analysis to determine significant associations.

Main Results:

  • Food (27.3%) and venom immunotherapy (VIT, 25%) were the most frequent triggers.
  • Respiratory (95.5%) and dermatological (90.9%) symptoms predominated.
  • Food-triggered anaphylaxis had a longer duration; one case of severe reaction to VIT required intensive care.

Conclusions:

  • Venom immunotherapy (VIT) is a significant trigger for anaphylaxis in children.
  • The high frequency of VIT-induced anaphylaxis warrants further investigation.
  • Comprehensive management strategies are essential for pediatric anaphylaxis.
Abstract

Keywords:
AnaphylaxisChildren

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