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Low energy intakes are associated with adverse outcomes in infants after open heart surgery
Bodil M K Larsen1, Laksiri A Goonewardene, Catherine J Field
1Nutrition Services, University of Alberta, Edmonton, Alberta, Canada.
Insights
Adequate energy intake is crucial for infants after open heart surgery. Insufficient nutrition (<63 kcal/kg/d) is linked to longer recovery times and increased complications in the pediatric intensive care unit.
Area of Science:
- Pediatric Critical Care Medicine
- Neonatal Surgery
- Nutritional Support
Background:
- Infants undergoing open heart surgery experience significant metabolic stress postoperatively.
- This stress can lead to altered metabolism and hypercatabolism.
- Understanding nutritional needs is vital for improving outcomes.
Purpose of the Study:
- To investigate the association between energy intake and hospital outcomes in neonates after open heart surgery.
- To determine the optimal energy threshold for recovery in the first 10 postoperative days.
Main Methods:
- Post hoc analysis of a prospective randomized controlled trial involving 32 infants.
- Assessment of nutrition intake and hospital outcomes in neonatal and pediatric intensive care units.
- Comparison of outcomes between infants receiving <689 kcal (average 63 kcal/kg/d) and ≥689 kcal during postoperative days 0-10.
Main Results:
- Lower energy intake (<63 kcal/kg/d) correlated with significantly longer mechanical ventilation duration (5 ± 1.2 days).
- Reduced energy intake was associated with increased time to chest closure (1.4 ± 0.5 days) and longer intensive care unit stays (5 ± 1.8 days).
- Infants with lower energy intake required longer parenteral nutrition support (8 ± 2.9 days) and experienced delays in achieving full enteral feeding.
Conclusions:
- Energy intake below 63 kcal/kg/d in the early postoperative period is linked to adverse outcomes in infants after open heart surgery.
- Optimal nutritional support is critical for mitigating complications and improving recovery trajectories.
- Findings highlight the importance of monitoring and optimizing energy delivery in this vulnerable population.
Background:
Infants with congenital heart lesions who undergo open heart surgery may experience physiologic and metabolic stress in the postoperative period, leading to altered metabolism and hypercatabolism. The purpose of this study was to determine the relationship between energy intake and hospital outcomes during the first 10 days following neonatal open heart surgery.
Materials And Methods:
A post hoc analysis of all patients in a prospective randomized controlled trial was performed. Nutrition intake and hospital outcomes were assessed in 32 infants (40 ± 2.2 weeks, 3.4 ± 0.5 kg) in the neonatal and pediatric intensive care units. Infants received parenteral nutrition (PN) for 1-4 days before and 10 days after open heart surgery. Infants were separated into those who received a cumulative energy intake of <689 kcal (average 63 kcal/kg/d) and those who received an intake ≥689 kcal during postoperative days 0-10.
Results:
Lower energy intake was associated with a significantly increased duration of artificial ventilation (5 ± 1.2 days), time to chest closure (1.4 ± 0.5 days), time in intensive care (5 ± 1.8 days), and stay in the hospital (25 ± 6.4 days). Lower energy intake was also associated with a significant increase in the length of time infants required PN (8 ± 2.9 days) and longer time to achieve full enteral intake of 100 mL/kg/d (7 ± 2.2 days) and before enteral feeds could be initiated (5 ± 1.5 days).
Conclusions:
Providing <63 kcal/kg/d to infants after open heart surgery was associated with adverse pediatric intensive care outcomes.
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