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Related Experiment Video

Updated: May 17, 2026

A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence

A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence

Published on: October 11, 2018

Spontaneous intestinal perforation.

Rizwan A Khan¹, Kannan L Narasimhan

¹Department of Surgery, JN Medical College, Aligarh, India. drrizwanahmadkhan@yahoo.cp.in

Annali Italiani Di Chirurgia

|October 16, 2012

Summary

This summary is machine-generated.

Necrotizing enterocolitis is a serious condition in premature infants. This case highlights a rare sign, pneumoscrotum, in diagnosing necrotizing enterocolitis perforation.

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A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence

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An Intravital Microscopy-Based Approach to Assess Intestinal Permeability and Epithelial Cell Shedding Performance

An Intravital Microscopy-Based Approach to Assess Intestinal Permeability and Epithelial Cell Shedding Performance

Published on: December 3, 2020

Area of Science:

Neonatology
Pediatric Surgery
Gastroenterology

Background:

Neonatal necrotizing enterocolitis (NEC) is a critical gastrointestinal emergency in neonates, predominantly affecting preterm infants with high mortality rates.
Classic NEC presentation includes abdominal distension, bloody stools, and pneumatosis intestinalis.
Diagnosis can be challenging due to atypical clinical signs and limitations of radiological features.

Observation:

A neonate presented with symptoms initially suggestive of an obstructed inguinal hernia.
The neonate's condition evolved, revealing a rare manifestation not typically associated with NEC.

Findings:

The case demonstrated necrotizing enterocolitis perforation.
Pneumoscrotum was identified as a rare presenting sign of NEC perforation in this neonate.
This finding underscores the diagnostic challenges in NEC, especially with atypical presentations.

Implications:

This case expands the spectrum of clinical presentations for necrotizing enterocolitis perforation.
Recognizing rare signs like pneumoscrotum is crucial for timely diagnosis and management of NEC.
Highlights the need for a comprehensive diagnostic approach beyond classic signs and standard imaging in neonates with abdominal emergencies.