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Updated: May 17, 2026

Analysis of Cell Migration within a Three-dimensional Collagen Matrix
Published on: October 5, 2014
Automated velocity mapping of migrating cell populations (AVeMap)
Maxime Deforet1, Maria Carla Parrini, Laurence Petitjean
1Laboratoire Physico-chimie Curie, Unité Mixte de Recherche 168, Centre de Recherche, Institut Curie, Centre National de la Recherche Scientifique, et Université Pierre et Marie Curie, Paris, France.
Abstract:
Characterizing the migration of a population of cells remains laborious and somewhat subjective. Advances in genetics and robotics allow researchers to perform many experiments in parallel, but analyzing the large sets of data remains a bottleneck. Here we describe a rapid, fully automated correlation-based method for cell migration analysis, compatible with standard video microscopy. This method allows for the computation of quantitative migration parameters via an extensive dynamic mapping of cell displacements.
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