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Cardiac angiosarcoma presenting with tamponade
Elie Chalhoub1, Bassam I Mattar, Wassim Shaheen
1Internal Medicine Department, The University of Kansas School of Medicine-Wichita, USA. echalhoub@kumc.edu
Primary cardiac angiosarcoma, a rare but common heart tumor, can cause heart failure. Early diagnosis is crucial, as prognosis is often poor despite treatment.
Area of Science:
- Cardiology
- Oncology
- Pathology
Background:
- Primary cardiac angiosarcoma is the most common primary malignant cardiac tumor, though rare overall.
- It can present insidiously, mimicking other conditions.
Observation:
- A 51-year-old man presented with acute right heart failure due to pericardial tamponade.
- Initial pericardiocentesis yielded bloody fluid with negative pathology.
- Echocardiography revealed a right atrial mass.
Findings:
- The patient was diagnosed with cardiac angiosarcoma.
- Despite surgery and chemotherapy, the patient died seven months post-diagnosis.
Implications:
- Cardiac angiosarcoma must be considered in the differential diagnosis of bloody pericardial effusions, even with initially negative investigations.
- The prognosis for cardiac angiosarcoma is typically poor.
- Treatment involves surgical resection, potentially combined with neoadjuvant/adjuvant chemotherapy, radiation, and immunotherapy.
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