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Related Experiment Video

Updated: May 17, 2026

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
10:18

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Published on: October 29, 2012

Recent developments in optical neuromodulation technologies.

Aron Kos1, Nikkie F Olde Loohuis, Jeffrey C Glennon

  • 1Department of Cognitive Neuroscience, Radboud University Nijmegen Medical Centre, 6525 EZ, Nijmegen, The Netherlands.

Molecular Neurobiology
|October 16, 2012
PubMed
Summary

Optogenetics enables precise control of neural circuits, advancing neuroscience research and understanding of brain function and disorders. This technology shows promise for future treatments of neuropsychiatric and neurodegenerative diseases.

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Area of Science:

  • Neuroscience
  • Molecular Biology
  • Biotechnology

Background:

  • Optogenetics offers advanced neural circuit interrogation beyond electrical stimulation.
  • It has rapidly yielded significant findings in normal brain function and disease states.

Purpose of the Study:

  • To provide an overview of recent optogenetics developments.
  • To highlight their relevance for understanding neuropsychiatric and neurodegenerative disorders.
  • To explore potential future therapeutic interventions.

Main Methods:

  • Utilizing optogenetics for targeted activation of specific axonal pathways.
  • Employing optogenetics in vivo to control diverse behavioral responses.
  • Leveraging an increasing variety of opsins for neuronal activity regulation.

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Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
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Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Published on: September 1, 2022

Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

Related Experiment Videos

Last Updated: May 17, 2026

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue
10:18

Fiber-optic Implantation for Chronic Optogenetic Stimulation of Brain Tissue

Published on: October 29, 2012

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording
06:36

Optrode Array for Simultaneous Optogenetic Modulation and Electrical Neural Recording

Published on: September 1, 2022

Optogenetic Functional MRI
06:06

Optogenetic Functional MRI

Published on: April 19, 2016

Main Results:

  • Optogenetics has facilitated breakthroughs in understanding neural networks.
  • In vivo studies have enabled control of complex behaviors in freely moving animals.
  • Development of diverse animal models has enhanced comprehension of behavior-associated neural networks.

Conclusions:

  • Optogenetics advancements are crucial for understanding brain disorders.
  • The technology holds significant potential for future therapeutic applications in human diseases.
  • Continued development of opsins broadens the scope of neuronal regulation.