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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
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Published on: July 1, 2020

Emerging systemic fungal infections.

Ricardo Galimberti1, Ana Clara Torre, María Carolina Baztán

  • 1Department of Dermatology, Hospital Italiano de Buenos Aires, Juan D. Peron 4190 (CP1181ACH), Buenos Aires, Argentina. ricardo.galimberti@hospitalitaliano.org.ar

Clinics in Dermatology
|October 17, 2012
PubMed
Summary
This summary is machine-generated.

Systemic mycoses caused by Aspergillus, Fusarium, and Penicillium species are increasing in immunocompromised individuals. Early diagnosis and appropriate antifungal treatment are crucial for managing these serious fungal infections.

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Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Dermatology

Background:

  • Systemic mycoses are diverse fungal infections impacting immunocompromised individuals.
  • Recent increases in incidence are linked to migration, AIDS, transplantation, and immunosuppressive therapies.
  • Key fungi implicated include Aspergillus spp., Fusarium spp., and Penicillium spp.

Purpose of the Study:

  • To outline the microbiological and epidemiological features of Aspergillus, Fusarium, and Penicillium.
  • To describe clinical manifestations requiring early dermatological diagnosis.
  • To detail diagnostic tools, prevention strategies, and antifungal treatments.

Main Methods:

  • Review of microbiological and epidemiological data for specified fungi.
  • Analysis of clinical presentations and diagnostic methods.
  • Evaluation of antifungal agents, including mechanism of action and efficacy.

Main Results:

  • Detailed characterization of Aspergillus, Fusarium, and Penicillium species.
  • Identification of clinical signs prompting early dermatological suspicion.
  • Comprehensive overview of diagnostic techniques and available antifungals.

Conclusions:

  • Increased incidence of systemic mycoses necessitates heightened awareness.
  • Early dermatological diagnosis is vital for effective management.
  • Understanding fungal characteristics and antifungal efficacy aids treatment strategies.