Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phases of Wound Repair01:28

Phases of Wound Repair

Following injury, the integrity of the injured tissues must be reestablished. For example, in skin tissue, wound repair involves coordination among resident skin cells, blood mononuclear cells, extracellular matrix, growth factors, and cytokines to complete the healing cascade.
Formation of Blood Clot
In case of deep injuries, trauma to blood vessels results in blood loss. In the meantime, phospholipids released from the ruptured endothelial cellular membrane are converted into arachidonic...
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the exudate's...
Aneurysm IV: Nursing Management01:22

Aneurysm IV: Nursing Management

Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canaloplasty and trabecular bypass glaucoma surgery: indications and outcomes.

Current opinion in ophthalmology·2026
Same author

Prospective Pilot Study of Sustained Release Bimatoprost Implant with SpyGlass Intraocular Lens: 3-Year Results.

Ophthalmology and therapy·2026
Same author

Histopathological Changes After Standard and Novel Endoscopic Cyclophotocoagulation versus Transscleral Cyclophotocoagulation in Human Cadaveric Eyes.

Clinical ophthalmology (Auckland, N.Z.)·2025
Same author

A Systematic Review of the PAUL Glaucoma Implant.

Clinical ophthalmology (Auckland, N.Z.)·2025
Same author

One year clinical outcomes with a novel canaloplasty device in mild to severe open angle glaucoma.

International journal of ophthalmology·2025
Same author

Acute Structural Effects of Novel Endoscopic Cyclophotocoagulation versus Standard Endoscopic and Transscleral Cyclophotocoagulation.

Clinical ophthalmology (Auckland, N.Z.)·2025
Same journal

Trends in pediatric uveitis: A systematic review and meta-epidemiological investigation of geographic, economic, and climate factors.

Survey of ophthalmology·2026
Same journal

Efficacy and safety of different intraocular therapies for non-infectious uveitis: A network meta-analysis.

Survey of ophthalmology·2026
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
See all related articles

Related Experiment Videos

Wound modulation after filtration surgery.

Leonard K Seibold1, Mark B Sherwood, Malik Y Kahook

  • 1Rocky Mountain Lions Eye Institute, Department of Ophthalmology, University of Colorado at Denver, Aurora, Colorado, USA.

Survey of Ophthalmology
|October 17, 2012
PubMed
Summary
This summary is machine-generated.

Filtration surgery for advanced glaucoma aims to lower intraocular pressure. New agents and techniques are being investigated to control wound healing and improve surgical success without increasing complications.

Related Experiment Videos

Area of Science:

  • Ophthalmology
  • Surgical Innovation
  • Wound Healing Biology

Background:

  • Filtration surgery is a standard treatment for advanced glaucoma to manage intraocular pressure.
  • Successful surgery relies on modulating the wound healing cascade that can close the new aqueous outflow pathway.
  • Current antifibrotic agents (mitomycin C, 5-fluorouracil) improve success but carry risks of complications.

Purpose of the Study:

  • To review novel agents and techniques for modulating wound healing after filtration surgery.
  • To identify methods that enhance surgical success while minimizing complications.
  • To explore alternatives to current antifibrotic therapies.

Main Methods:

  • Review of current literature on wound modulation in glaucoma filtration surgery.
  • Analysis of novel antifibrotic agents and surgical techniques under investigation.
  • Discussion of the mechanisms of action and potential benefits/risks of new approaches.

Main Results:

  • Several new agents and techniques are being explored to control the wound healing response.
  • These novel approaches aim to optimize aqueous outflow and reduce the risk of surgical failure.
  • The focus is on achieving better outcomes with an improved safety profile.

Conclusions:

  • Controlling wound healing is critical for the long-term success of glaucoma filtration surgery.
  • Novel therapeutic strategies are emerging to improve surgical outcomes and patient safety.
  • Further research is needed to validate the efficacy and safety of these new methods.