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Related Concept Videos

Techniques of therapeutic communication I: Active Listening, Sharing Observations, Validation, and Using Touch01:15

Techniques of therapeutic communication I: Active Listening, Sharing Observations, Validation, and Using Touch

The history of therapeutic communication can be traced back to Florence Nightingale, who emphasized the importance of developing trusting relationships with patients. She taught that the presence of nurses with patients results in therapeutic healing.
Therapeutic communication is not the same as social interaction. Social interaction has no goal or purpose and consists of casual information sharing, whereas therapeutic communication has a plan or purpose for the conversation. Therapeutic...
Psychodynamic Therapy01:29

Psychodynamic Therapy

Psychodynamic therapies emphasize the exploration of unconscious processes and early childhood experiences as fundamental contributors to psychological difficulties. These therapies, deeply rooted in Freud's psychoanalytic theory, aim to uncover and resolve unconscious conflicts, granting individuals insights that promote emotional and behavioral healing. Contemporary psychodynamic approaches have evolved, integrating a broader range of influences and methodologies while still valuing the...
Therapeutic Communication01:30

Therapeutic Communication

Communication is a lifelong learning process. Through therapeutic communication, nurses can collect relevant assessment data, provide education and counseling, and interact during nursing interventions. Sending and receiving messages occur through verbal and nonverbal communication techniques and can happen separately or simultaneously.
Verbal communication depends on language or a prescribed way of using words so that people can share information effectively. The critical aspects of verbal...
Psychotherapy01:28

Psychotherapy

Psychotherapy is a versatile, nonmedical approach aimed at helping individuals address emotional, behavioral, and interpersonal issues to enhance their overall well-being. It can involve one-on-one sessions, couples counseling, or small group discussions with a therapist. The therapeutic process includes various techniques such as open discussion, interpretation of thoughts and behaviors, active listening, positive reinforcement, and role modeling. Psychotherapy aims to support individuals in...
Humanistic Therapy01:24

Humanistic Therapy

Humanistic therapies emphasize personal growth, self-understanding, and the fulfillment of human potential. Rooted in the belief that individuals inherently strive toward self-actualization, these approaches encourage clients to explore their feelings and experiences in a supportive, nonjudgmental environment. Humanistic therapies differ from psychodynamic approaches by focusing on conscious experiences, present circumstances, and the potential for self-improvement rather than past conflicts...
Techniques of Therapeutic Communication II: Focusing, Paraphrasing, and Summarizing01:23

Techniques of Therapeutic Communication II: Focusing, Paraphrasing, and Summarizing

Focusing involves centering a conversation on a message's critical elements or concepts. Focusing is valuable if the talk is vague or patients begin to repeat themselves. Sometimes, when patients are asked about their symptoms, they may go off-topic and try to tell their entire life story. Respectfully, the nurse should bring the conversation back into focus.
This therapeutic technique can also be used when a patient brings up pertinent information during a health-related conversation. The...

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Published on: January 7, 2020

Exploring the therapeutic space around NAD+.

Riekelt H Houtkooper1, Johan Auwerx

  • 1Laboratory Genetic Metabolic Diseases, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands. r.h.houtkooper@amc.nl

The Journal of Cell Biology
|October 17, 2012
PubMed
Summary
This summary is machine-generated.

Maintaining cellular NAD(+) levels is key to preventing metabolic diseases and age-related decline. Research into NAD(+) signaling pathways offers new clinical treatments for these conditions.

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Area of Science:

  • Biochemistry
  • Cellular Metabolism
  • Aging Research

Background:

  • Nicotinamide adenine dinucleotide (NAD(+)) is a crucial cellular metabolite.
  • Altered NAD(+) levels and sirtuin activity are implicated in metabolic diseases (obesity, diabetes), cancer, and neurodegeneration.
  • NAD(+) plays a central role in cellular energy and signaling pathways.

Purpose of the Study:

  • To explore the role of NAD(+) in metabolic health and aging.
  • To discuss the therapeutic potential of modulating NAD(+) levels.
  • To highlight the clinical translation of NAD(+) signaling pathway discoveries.

Main Methods:

  • Review of current scientific literature on NAD(+) metabolism and signaling.
  • Analysis of the link between NAD(+) homeostasis and age-related diseases.
  • Examination of clinical studies investigating NAD(+) boosting strategies.

Main Results:

  • Maintaining or increasing NAD(+) levels can enhance metabolism.
  • Adequate NAD(+) is associated with improved mitochondrial function and reduced inflammation.
  • NAD(+) boosting strategies show promise in preclinical and early clinical settings.

Conclusions:

  • NAD(+) metabolism is a critical target for treating metabolic disorders and age-related diseases.
  • Therapeutic interventions aimed at NAD(+) homeostasis offer a promising avenue for clinical application.
  • Further research and clinical trials are essential to fully realize the potential of NAD(+)-based therapies.