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Effects of Desmodium caudatum on Gastrointestinal Hormones and Intestinal Flora in Rats with Gastritis

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Gastritis and mental disorders.

Renee D Goodwin¹, Robert A Cowles, Sandro Galea

¹Department of Psychology, Queens College, City University of New York, Flushing, NY 11367, USA. rdg66@columbia.edu

Journal of Psychiatric Research

|October 18, 2012

Summary

This summary is machine-generated.

Physician-diagnosed gastritis is linked to higher rates of mood and anxiety disorders in adults. This association was consistent across both sexes in a large population-based study.

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Effects of Desmodium caudatum on Gastrointestinal Hormones and Intestinal Flora in Rats with Gastritis

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Area of Science:

Gastroenterology
Psychiatry
Epidemiology

Background:

Previous research suggests links between gastrointestinal disorders and mood/anxiety issues.
However, the specific relationship between gastritis and these mental health conditions in the general population remains understudied.

Purpose of the Study:

To investigate the association between physician-diagnosed gastritis and mood and anxiety disorders in adults.
To explore potential sex differences in this relationship.

Main Methods:

Utilized data from a representative sample of 4181 adults (aged 18-79) from the German National Health Interview and Examination Survey.
Analyzed the prevalence of DSM-IV mood and anxiety disorders in individuals with and without a gastritis diagnosis.

Main Results:

Adults with gastritis showed significantly higher rates of anxiety disorders (27.0% vs. 15.3%) and affective disorders (20.1% vs. 11.5%).
Gastritis diagnosis was associated with increased odds of panic attacks, social phobia, major depression, and any mood disorder.
No significant sex differences were observed in these associations.

Conclusions:

Physician-diagnosed gastritis is significantly associated with increased odds of mood and anxiety disorders in the general adult population.
The observed relationship between gastritis and mental health conditions was consistent between males and females, contrasting with some animal study findings.