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Folding and Characterization of a Bio-responsive Robot from DNA Origami
Published on: December 3, 2015
Clear-cut observation of PNA invasion using nanomechanical DNA origami devices
Takahiro Yamazaki1, Yuichiro Aiba, Kohei Yasuda
1RCAST, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo 153-8904, Japan.
Chemical Communications (Cambridge, England)
|October 18, 2012
Abstract:
Invasive binding event of PNA into DNA duplex was clearly observed both by atomic force microscope (AFM) imaging and electrophoretic mobility shift assay (EMSA) with the aid of nanomechanical DNA origami devices as 'single-molecule' visual probes, showing their potential as universal platform for the analysis of PNA invasion.
