Diagnosis and treatment of osteopenic fractures in children

Charles T Mehlman1, Marcia A Shepherd, Carie S Norris

  • 1Division of Pediatric Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, OH 45229-2017, USA. Charles.Mehlman@cchmc.org

Insights

Pediatric osteopenic fractures are common, occurring even in healthy or obese children. This review examines recent research on managing these fractures, particularly in genetic conditions like osteogenesis imperfecta and neurofibromatosis.

Area of Science:

  • Pediatric orthopedics
  • Pediatric bone health
  • Skeletal disorders in children

Background:

  • Osteopenic fractures are a daily occurrence in children, sometimes evident in genetic conditions like neurofibromatosis and osteogenesis imperfecta.
  • In many cases, such as in normal or obese children, the osteopenic nature of fractures is not overtly apparent.
  • Normal pediatric bone development includes phases of relative weakness, and childhood obesity can exacerbate this by overwhelming bone's adaptive capacity.

Purpose of the Study:

  • To review recent research on pediatric osteopenic fractures.
  • To highlight the challenges posed by genetic conditions and obesity in pediatric bone health.
  • To provide radiographic examples of fracture treatment.

Main Methods:

  • Literature review of recent research on pediatric osteopenic fractures.
  • Analysis of conditions predisposing children to osteopenia, including genetic disorders and obesity.
  • Radiographic case study examples of fracture management.

Main Results:

  • Osteopenic fractures present a significant clinical challenge in pediatrics.
  • Genetic conditions (e.g., osteogenesis imperfecta, neurofibromatosis) and obesity are key factors contributing to pediatric osteopenia and fractures.
  • Effective treatment strategies exist and are illustrated through radiographic examples.

Conclusions:

  • Understanding the varied causes of pediatric osteopenia is crucial for effective fracture management.
  • Recent research offers insights into addressing bone weakness in children.
  • Radiographic evidence supports various treatment approaches for osteopenic fractures in pediatric populations.

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Remodeling and Repair01:31

Bone Remodeling and Repair

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...