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Related Experiment Video

Updated: May 17, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

ImProving Outcomes after STroke (POST): results from the randomized clinical pilot trial.

Maree L Hackett1, Greg Carter, Denis Crimmins

  • 1The George Institute for Global Health, The University of Sydney, Sydney, NSW, Australia.

International Journal of Stroke : Official Journal of the International Stroke Society
|October 19, 2012
PubMed
Summary

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A postcard intervention after stroke did not significantly reduce depression rates. However, the postcards effectively engaged patients post-discharge, suggesting potential for improved patient connection.

Area of Science:

  • Neurology
  • Psychiatry
  • Public Health

Background:

  • Post-stroke depression affects one in three patients.
  • There is a need for cost-effective, low-risk interventions to prevent post-stroke depression.

Purpose of the Study:

  • To evaluate the effectiveness of a monthly postcard intervention in preventing depression after stroke.

Main Methods:

  • A randomized trial compared a five-month monthly postcard intervention plus usual care to usual care alone in patients post-stroke.
  • Participants (n=100 intervention, n=101 control) were assessed at six months.

Main Results:

  • No significant difference in depression rates between the postcard intervention group (1/88) and the control group (3/76).
Keywords:
clinical trialinterventionischemic strokepreventionstroketherapy

Related Experiment Videos

Last Updated: May 17, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
08:53

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke

Published on: June 6, 2025

  • No significant differences observed in Hospital Anxiety and Depression Scale (HADS) scores, quality of life, or daily living activities.
  • A positive response rate of 47% to the postcards was noted.

    • Conclusions:

    • The postcard intervention did not significantly reduce depression scores after stroke.
    • The intervention showed potential as an engaging method for connecting with patients post-hospital discharge.