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Updated: May 17, 2026

Surgical Procedures and Methodology for a Preclinical Murine Model of De Novo Mammary Cancer Metastasis
Published on: July 29, 2017
First case of isolated vaginal metastasis from breast cancer treated by surgery
Filippo Bellati1, Innocenza Palaia, Maria Luisa Gasparri
1Department of Gynecology and Obstetrics, "Sapienza" University of Rome, Viale Regina Elena 324, 00161, Rome, Italy. filippo.bellati@uniroma1.it
Background:
Breast cancer is a leading cause of death in developed countries. This neoplasm frequently relapses at distant sites such as bone, lung, pleura, brain and liver but rarely in the lower female genital tract.
Case Presentation:
We present the first case of isolated vaginal breast cancer metastasis and its surgical treatment.
Conclusion:
This case report focuses on the importance of an accurate genital tract examination as part of regular follow up in breast cancer survivors. Indeed, after this experience we feel that surgery could be considered a valid option for the treatment of an isolated vaginal metastasis.
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