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Updated: May 17, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
Venous thromboprophylaxis in pregnancy: the implications of changing to the 2010 RCOG guidelines
D Touqmatchi1, C Cotzias, J Girling
1Department of Obstetrics and Gynaecology, West Middlesex University Hospital NHS Trust, Isleworth, Middlesex, UK. dana_touqmatchi@hotmail.com
Abstract:
The latest Confidential Enquiry into Maternal Deaths (2006-2008) shows that venous thromboembolism (VTE) is now the third leading cause of direct maternal mortality, behind sepsis and hypertension. This is likely to be because of improved risk assessment of patients and adequate thromboprophylaxis both antenatally and postnatally. Given the importance of this area, compliance with the departmental VTE guidelines (which were based on previous RCOG guidelines) was reviewed prior to transferring to a revised guideline based on the recent RCOG guideline (2010). The results obtained highlighted the difficulties in achieving good VTE risk assessment, with only 60% of patients being adequately assessed and managed antenatally, and 68% postnatally. The findings led to a revised guideline, and it was anticipated that this change would facilitate improved compliance. Other units are likely to be facing similar difficulties, and therefore these results also aim to encourage others to consider review and assessment of their own VTE risk assessment protocols.
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