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Updated: May 17, 2026
10:28
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Gastric neuroendocrine tumours
David A Crosby1, Claire L Donohoe, Louise Fitzgerald
1Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin/St James's Hospital, Dublin, Ireland.
Digestive Surgery
|October 19, 2012
Summary
Gastric neuroendocrine tumors (NETs) are increasingly diagnosed, with management guided by prognostic groups and evolving treatment strategies. Individualized care by multidisciplinary teams is crucial for these diverse tumors.
Area of Science:
- Gastroenterology
- Oncology
- Endocrinology
Background:
- Gastric neuroendocrine tumors (NETs) recognition is growing.
- Management challenges stem from incomplete understanding of etiology, natural history, and optimal therapy.
- This review synthesizes recent advances in epidemiology, classification, molecular profiling, and treatment.
Purpose of the Study:
- To present a current understanding of gastric neuroendocrine tumors.
- To outline recent advances in their epidemiology, classification, molecular profiling, and treatment.
- To guide clinical decision-making for gastric NETs.
Main Methods:
- Literature search of PubMed and relevant cited articles.
- Selection based on peer review, journal reputation, and relevance.
- Synthesis of current knowledge on gastric NETs.
Main Results:
- Gastric NETs classified into three prognostic groups (Type I, II, III) based on etiology and metastatic potential.
- Reported frequency of gastric NETs has increased.
- Management strategies have advanced with improved endoscopic staging, surgery, and biological understanding.
Conclusions:
- Gastric NETs exhibit a range from indolent to metastatic disease.
- Individualized treatment plans managed by multidisciplinary teams are essential.
- Limited evidence necessitates treatment within expert clinical networks.
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