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Related Concept Videos

Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Video

Updated: May 17, 2026

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments
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SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

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A descriptive study to characterize segmental vitiligo.

Binod K Khaitan1, Sushruta Kathuria, M Ramam

  • 1Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2012
PubMed
Summary
This summary is machine-generated.

Segmental vitiligo, often resistant to medical treatment, shows distinct clinical features. Early onset, blaschkoid patterns, and specific lesion characteristics aid in diagnosing this unique vitiligo subset.

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Published on: March 9, 2015

Area of Science:

  • Dermatology
  • Clinical Research

Background:

  • Segmental vitiligo is a distinct subtype of vitiligo.
  • It shows poor response to medical therapies but good response to surgical interventions.
  • Understanding its pattern may elucidate disease pathogenesis.

Purpose of the Study:

  • To clinically characterize the features of segmental vitiligo.
  • Study conducted at AIIMS dermatology outpatient department.

Main Methods:

  • Cross-sectional clinical study.
  • Evaluated 188 consecutive patients.
  • Data collected via history, clinical examination, and photography.

Main Results:

  • Characteristic features include early onset and initial progression followed by stability.
  • Blaschkoid pattern, irregular margins, and leucotrichia (white hair) are common.
  • Islands of pigmented macules within lesions were also noted.

Conclusions:

  • A combination of early onset, blaschkoid pattern, irregular margins, leucotrichia, and pigmented macules aids in diagnosis.
  • These features are crucial for identifying segmental vitiligo.