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Updated: May 17, 2026

Integration of Wet and Dry Bench Processes Optimizes Targeted Next-generation Sequencing of Low-quality and Low-quantity Tumor Biopsies
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Next-generation sequencing in the clinic: are we ready?

Leslie G Biesecker1, Wylie Burke, Isaac Kohane

  • 1Genetic Disease Research Branch, National Human Genome Research Institute, 49 Convent Drive, Room 4A56, Bethesda, Maryland 20892, USA. lesb@helix.nih.gov

Nature Reviews. Genetics
|October 19, 2012
PubMed
Summary

Clinical whole-genome and targeted sequencing offer powerful insights but require improved infrastructure. Experts discuss managing genomic data and enhancing patient care.

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