Gain in lung function after weight reduction in severely obese children
E J van de Griendt1, O H van der Baan-Slootweg, E E M van Essen-Zandvliet
1Department of Pediatric Respiratory Medicine and Allergy, Emma Children's Hospital, Academic Medical Centre, Amsterdam, The Netherlands. e.j.vandegriendt@amc.nl
Insights
Weight loss in severely obese children significantly improved lung function, particularly expiratory reserve volume (ERV). This improvement correlated with reduced BMI and waist circumference, highlighting the benefits of weight management programs.
Area of Science:
- Pediatrics
- Pulmonology
- Obesity Research
Background:
- Extreme obesity in children poses significant health risks, including potential impacts on respiratory health.
- Understanding the effects of weight management interventions on pediatric pulmonary function is crucial for long-term health outcomes.
Purpose of the Study:
- To investigate the impact of a structured weight loss program on pulmonary function in extremely obese children.
- To determine the correlation between weight reduction and specific lung function parameters.
Main Methods:
- A prospective cohort study involving 112 extremely obese children undergoing a 26-week multidisciplinary treatment program.
- Pulmonary function tests and measurements of waist circumference were conducted at baseline and after the intervention period.
Main Results:
- Significant improvements were observed in functional vital capacity, forced expiratory volume in 1 second (FEV1), total lung capacity, and expiratory reserve volume (ERV).
- Expiratory reserve volume (ERV) showed a notable increase of 14.8%, strongly correlating with reductions in BMI (SDS-BMI) and waist circumference.
- Improvements in FEV1 did not show a significant correlation with BMI or waist circumference reduction.
Conclusions:
- Weight loss interventions in severely obese children lead to measurable improvements in lung function.
- The enhancement in expiratory reserve volume (ERV) is particularly linked to successful weight reduction, as indicated by decreased BMI and waist circumference.
Aim:
The primary objective of this prospective cohort study was to determine the effect of weight loss on pulmonary function values in extremely obese children.
Methods:
Obese children participated in a 26-week in-hospital or outpatient multidisciplinary treatment programme. Waist circumference was measured and pulmonary function tests were performed at enrolment and after 6 months.
Results:
The data of 112 children were analysed. The children had a mean age of 14.4 (range 8.5-18.9) years and 62.5% were girls. The mean SD score-body mass index (SDS-BMI) was +3.38 at baseline and +2.91 after the intervention. Lung function improved significantly: functional vital capacity increased by 3.08% (95% CI 1.16% to 5.00%) of the predicted value, forced expiratory volume in 1 s (FEV(1)) by 2.91% (95% CI 1.11% to 4.71%) of the predicted value, total lung capacity by 2.27% (95% CI 1.16% to 5.00%) of the predicted value, and expiratory reserve volume (ERV) by 14.8% (95% CI 8.66% to 20.88%) of the predicted value. The increase in ERV correlated with the reduction in SDS-BMI and with the reduction in waist circumference. FEV(1) did not correlate with the reduction in either SDS-BMI or waist circumference.
Conclusions:
Weight loss in severely obese children correlated with an improvement in lung function, especially ERV. The improvement in ERV correlated with the decrease in SDS-BMI and waist circumference.
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