Latent class analysis reveals five homogeneous behavioural and developmental profiles in a large Dutch population
Esmé Möricke1, G A Martijn Lappenschaar, Sophie H N Swinkels
1Department of Psychiatry (966), Nijmegen Centre for Evidence-Based Practice, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands. e.moricke@psy.umcn.nl
Insights
Early identification of child psychiatric disorders is possible. Distinct behavioral and developmental profiles in infants aged 14-15 months can predict later issues, aiding early detection and treatment.
Area of Science:
- Child psychiatry
- Developmental psychology
- Behavioral science
Background:
- Child psychiatric disorders often have precursors in infancy.
- Limited understanding of general psychopathology prevalence and course in infants (0-3 years).
Purpose of the Study:
- Identify homogeneous behavioral and developmental profiles in 14-15-month-old infants.
- Explore correspondence of these profiles with existing classifications (DSM-IV-TR, ICD-10, DC 0-3R).
Main Methods:
- Population-based sample of 6,330 infants (aged 14-15 months).
- Parental questionnaires on externalizing, internalizing, and social-communicative behaviors (74 items).
- Exploratory factor analysis and latent class analysis.
Main Results:
- Nine behavioral factors identified, including communication, emotionality, and social interaction problems.
- Five distinct infant profiles emerged; three linked to increased problems.
- Specific profiles aligned with multisystem developmental disorders, anxiety, mood, pervasive developmental, communication, language, speech, regulation, attention-deficit, disruptive behavior, hyperkinetic, and conduct disorders.
Conclusions:
- Distinct behavioral and developmental profiles are recognizable in infancy.
- This approach supports longitudinal research on profile stability.
- Facilitates early detection, diagnosis, and treatment of infant behavioral and developmental issues.
Abstract:
Precursors of child psychiatric disorders are often present in infancy, but little is known about the prevalence and course of general psychopathology in population-based samples of children 0-3 years. We examined whether homogeneous behavioural and developmental profiles could be identified in children aged 14-15 months (M = 14.84; SD = 2.19), and we explored whether or not these profiles corresponded with existing classifications of DSM-IV-TR, ICD-10, and DC 0-3R. Parents of 6,330 children answered 74 items about externalizing, internalizing, and social-communicative behaviour. Exploratory factor analysis revealed nine factors: deviant communication, negative emotionality, deviant reactive behaviour, deviant play behaviour, demanding behaviour, social anxiety/inhibition, advanced social interaction problems, basic social interaction problems, and sleep problems. Latent class analysis yielded five profiles, of which three were associated with increased behavioural and developmental problems. Some infants (5.7 %) had communication and social interaction problems corresponding to multisystem developmental disorders (DC 0-3R) and suggestive of anxiety, mood, or pervasive developmental disorders (DSM-IV-TR, ICD-10). Other infants (16.4 %) had communication problems, possibly precursors of communication, language, or speech disorders (DSM-IV-TR, ICD-10). Yet other infants (10.8 %) showed negative and demanding behaviour suggestive of regulation disorders (DC 0-3R), attention-deficit and disruptive behaviour disorders (DSM-IV-TR), or hyperkinetic and conduct disorders (ICD-10). Thus, even in infancy certain distinct behavioural and developmental profiles can be recognized. This combined approach will enable follow-up research into the stability of factors, classes, and profiles over time, and will facilitate early detection, diagnosis, and treatment of behavioural and developmental problems.
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