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Body-composition reference data for simple and reference techniques and a 4-component model: a new UK reference child
Jonathan C K Wells1, Jane E Williams, Sirinuch Chomtho
1Childhood Nutrition Research Centre, University College London Institute of Child Health, London, United Kingdom. jonathan.wells@ucl.ac.uk
Insights
This study provides essential body composition reference data for children aged 4-20. These new charts and standard deviation scores (SDSs) will aid clinicians in assessing pediatric body composition accurately.
Area of Science:
- Pediatric Health
- Body Composition Analysis
- Clinical Reference Standards
Background:
- Routine pediatric body composition assessment is recommended but limited by a lack of appropriate techniques and reference data.
- Existing measurement techniques are improving, but standardized reference data for interpretation remains a critical need.
Purpose of the Study:
- To establish comprehensive body composition reference data for pediatric populations.
- To support clinical practice and research by providing interpretable measurement standards.
Main Methods:
- Utilized a gold standard 4-component model and various widely used methods to measure body composition in a representative sample of British children (aged 4-20 years).
- Included anthropometric variables, dual-energy X-ray absorptiometry, body density, bioelectrical impedance, and total body water measurements.
- Calculated 4-component fat and fat-free masses, constructing reference charts and standard deviation scores (SDSs) using the lambda-mu-sigma method for fat-free mass index and fat mass index.
Main Results:
- Developed body composition growth charts and SDSs for ages 5-20 years based on data from 533 individuals.
- Demonstrated strong correlations between SDSs from different techniques (≥0.68 for adiposity, ≥0.80 for fat-free mass).
Conclusions:
- The generated reference data are comprehensive and applicable across various pediatric body composition measurement techniques.
- These data, combined with technological advancements, are expected to significantly improve the clinical assessment and monitoring of body composition in children.
- Facilitates more robust body composition measurements in pediatric research studies.
Background:
A routine pediatric clinical assessment of body composition is increasingly recommended but has long been hampered by the following 2 factors: a lack of appropriate techniques and a lack of reference data with which to interpret individual measurements. Several techniques have become available, but reference data are needed.
Objective:
We aimed to provide body-composition reference data for use in clinical practice and research.
Design:
Body composition was measured by using a gold standard 4-component model, along with various widely used reference and bedside methods, in a large, representative sample of British children aged from 4 to ≥20 y. Measurements were made of anthropometric variables (weight, height, 4 skinfold thicknesses, and waist girth), dual-energy X-ray absorptiometry, body density, bioelectrical impedance, and total body water, and 4-component fat and fat-free masses were calculated. Reference charts and SD scores (SDSs) were constructed for each outcome by using the lambda-mu-sigma method. The same outcomes were generated for the fat-free mass index and fat mass index.
Results:
Body-composition growth charts and SDSs for 5-20 y were based on a final sample of 533 individuals. Correlations between SDSs by using different techniques were ≥0.68 for adiposity outcomes and ≥0.80 for fat-free mass outcomes.
Conclusions:
These comprehensive reference data for pediatric body composition can be used across a variety of techniques. Together with advances in measurement technologies, the data should greatly enhance the ability of clinicians to assess and monitor body composition in routine clinical practice and should facilitate the use of body-composition measurements in research studies.
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