Related Experiment Video
Updated: May 17, 2026

A Laboratory Method to Measure Contagious Yawning in Rats
Published on: June 14, 2019
Pathological yawning as an ictal seizure manifestation in the elderly
Alessia Nicotra1, Nofal M Khalil, P Owbridge
1Department of Clinical Neurophysiology, Imperial College Healthcare NHS Trust, London, UK. a.nicotra@imperial.ac.uk
Abstract:
Excessive yawning has been reported in the peri-ictal period preceding or following seizures. We describe an exceptional case of an elderly man with impairment of consciousness and paroxysmal excessive yawning. We hypothesise that this can be regarded as an autonomic seizure originating from diencephalic/brainstem structures, manifesting with yawning as an ictal phenomenon.
Insights
Excessive yawning can signal seizures, particularly in elderly individuals with consciousness impairment. This case suggests paroxysmal yawning may represent an autonomic seizure originating in the brainstem.
Area of Science:
- Neurology
- Epileptology
- Autonomic Nervous System
Background:
- Excessive yawning is a known peri-ictal phenomenon associated with seizures.
- The diagnostic and prognostic significance of yawning in epilepsy requires further elucidation.
Observation:
- A case of an elderly male patient presented with impaired consciousness and paroxysmal excessive yawning.
- The yawning episodes occurred without other typical seizure manifestations.
Findings:
- The authors hypothesize that paroxysmal excessive yawning can be considered an autonomic seizure.
- This seizure type may originate from diencephalic or brainstem structures.
- Yawning served as the primary ictal phenomenon in this case.
Implications:
- This case expands the spectrum of ictal phenomena in epilepsy.
- It highlights the importance of considering autonomic seizures in patients with unexplained paroxysmal excessive yawning.
- Further research into diencephalic and brainstem seizure origins is warranted.
Related Concept Videos
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types
Seizures l: Introduction
Epilepsy ll: Types
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...

