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Updated: May 17, 2026

Identification of Hemolytic and Phospholipase Activity in Crude Extracts from Sea Anemones by Straightforward Bioassays
Published on: March 29, 2022
Cytotoxic petrosiacetylenes from the marine sponge Petrosia sp
Yeon-Ju Lee1, Su-Jung Yoo, Jong Soon Kang
1Korea Institute of Ocean Science and Technology, Ansan, Republic of Korea. yjlee@kiost.ac
Abstract:
A novel petrosiacetylene analog (petrosiacetylene E) has been isolated from the Korean marine sponge Petrosia sp., along with petrosiacetylene A, B and C. Their structures were elucidated on the basis of spectroscopic methods and the stereochemistry of the new compound was determined by using the modified Mosher's method. Petrosiacetylene E showed higher cytotoxicity against five human cancer cell lines than petrosiacetylene A and B, presumably due to the additional hydroxy group located at C-16.
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