Related Experiment Video
Updated: May 17, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
In vitro antibacterial activity of different self-etch adhesives
Claudio Poggio1, Carla Renata Arciola, Sergey Cepurnykh
1Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, School of Dentistry, University of Pavia, Pavia, Italy. claudio.poggio@unipv.it
Purpose:
The aim of this study was to evaluate and compare the antimicrobial activity of different self-etch adhesives by means of the agar disc diffusion test.
Methods:
Streptococcus salivarius, Streptococcus sanguis and Streptococcus mutans strains were selected to evaluate the antimicrobial activity of various self-etch adhesives (Futurabond NR, G-aenial Bond, Adper™ Easy Bond Self-Etch Adhesive, Clearfil Protect Bond, One Coat 7.0, Clearfil S3 Bond, Clearfil SE Bond) using the agar disc diffusion test; 0.2% Chlorexidine digluconate was used as control. Paper disks were saturated with 10 µL of each adhesive system and placed onto culture agar plates pre-adsorbed with bacterial cells and further incubated for 24 h at 37°C. The growth inhibition zones around each adhesive were recorded and compared for each bacterial strain.
Results:
The test results of the various self-etch adhesives were significantly different.
Conclusions:
The results of the present investigation showed that the addition of MDPB monomer to an adhesive system enhances its antibacterial effect against S. salivarius, S. sanguis and S. mutans.
