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Related Concept Videos

Continuing Care01:25

Continuing Care

Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care evaluation by...
Cancer Survival Analysis01:21

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Nursing Evaluation01:15

Nursing Evaluation

The evaluation stage signals the end of the nursing process. The nurse gathers evaluative data to assess whether or not the patient has attained the expected results. Whereas the nurse collects data in the nursing assessment to identify the patient's health concerns, the evaluation stage data determines if the indicated health issues are resolved. Evaluative data collection includes two sections: the data acquired to evaluate patient outcomes and the time criteria for data collection.
Section...
Kaplan-Meier Approach01:24

Kaplan-Meier Approach

The Kaplan-Meier estimator is a non-parametric method used to estimate the survival function from time-to-event data. In medical research, it is frequently employed to measure the proportion of patients surviving for a certain period after treatment. This estimator is fundamental in analyzing time-to-event data, making it indispensable in clinical trials, epidemiological studies, and reliability engineering. By estimating survival probabilities, researchers can evaluate treatment effectiveness,...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...

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Related Experiment Videos

Outcome measures for palliative care research.

Meera Agar1, Tim Luckett

  • 1Discipline of Palliative and Supportive Services, Flinders University, Adelaide, Australia. meera.agar@sswahs.nsw.gov.au

Current Opinion in Supportive and Palliative Care
|October 20, 2012
PubMed
Summary

This review highlights validated outcome measures for palliative care clinical trials, emphasizing their robustness and clinical meaningfulness. Emerging consensus and potential for composite measures can improve comparability and efficiency in end-of-life care research.

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Area of Science:

  • Palliative care research
  • Outcome measurement in clinical trials
  • End-of-life care domains

Background:

  • Palliative care interventions require rigorous outcome assessment.
  • Existing literature lacks a consolidated view of measurement progress.
  • Standardization is needed for comparing trial results and clinical practice.

Purpose of the Study:

  • To review the current state of science regarding physical symptoms and other end-of-life care outcomes in palliative care.
  • To summarize progress in the development and interpretation of outcome measures within the palliative care clinical trial context.

Main Methods:

  • Systematic review of literature on outcome measures in palliative care clinical trials.
  • Analysis of validated measures across various end-of-life care domains.
  • Assessment of measure interpretability and clinical meaningfulness.

Main Results:

  • Validated measures exist for a broad range of palliative care outcomes, ensuring robust and clinically meaningful trial results.
  • Emerging consensus facilitates outcome measure consolidation and potential extension into routine clinical practice.
  • Composite measures prioritizing patient-reported outcomes offer improved comparability and efficiency; adverse events require rigorous measurement.

Conclusions:

  • Clinical trials in palliative care must consider diverse outcomes.
  • The selection and timing of primary outcome measurement should align with the intervention's likely impact.
  • Further development and application of validated, patient-centered measures are crucial for advancing palliative care research and practice.