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Updated: May 17, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Acquired factor V inhibitor developing in a patient with esophageal squamous cell carcinoma
Minoo Ahmadinejad, Ahmadinejad Minoo1, Nader Roushan
1Reference Coagulation Laboratory, Iranian Blood Transfusion Organization Research Center, Tehran University of Medical Sciences, Tehran, Iran. minooam@gmail.com
Abstract:
An 82-year-old man referred to our medical ward because of epistaxis and melena was found to have 12 Bethesda units of factor V inhibitor. He was managed for bleeding with supportive care, followed by corticosteroid therapy. The bleeding completely stopped 1 week after corticosteroid therapy. Medical history revealed dysphagia during the past 6 months and further evaluation brought to light a squamous cell carcinoma (SCC) in the esophagus. This is the first case of an acquired factor V inhibitor developing in a patient with esophageal SCC without any other risk factors such as surgery.
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