Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Randomized Experiments01:13

Randomized Experiments

The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Blinding01:11

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Research objectives and general considerations for pragmatic clinical trials of pain treatments: IMMPACT statement.

Pain·2023
Same author

Yoga Versus Education for Veterans with Chronic Low Back Pain: a Randomized Controlled Trial.

Journal of general internal medicine·2023
Same author

Theory of Planned Behavior and Mindfulness Intentions in Chronic Low Back Pain.

Mindfulness·2022
Same author

Optimizing Narrowband UVB Phototherapy: Is It More Challenging for Your Older Patients?

Cutis·2022
Same author

Moderators and Nonspecific Predictors of Treatment Benefits in a Randomized Trial of Mindfulness-Based Stress Reduction vs Cognitive-Behavioral Therapy vs Usual Care for Chronic Low Back Pain.

The journal of pain·2022
Same author

An experimental study to inform adoption of mindfulness-based stress reduction in chronic low back pain.

Implementation science communications·2022
Same journal

RETRACTION: Isolation of Antidiabetic Principle from Fruit Rinds of <i>Punica granatum</i>.

Evidence-based complementary and alternative medicine : eCAM·2026
Same journal

RETRACTION: Molecular Mechanism of Traditional Chinese Ointment of Xuzhou Qufu Shengji in Infected Wounds.

Evidence-based complementary and alternative medicine : eCAM·2026
Same journal

RETRACTION: Involvement of Endoplasmic Reticulum Stress in Capsaicin-Induced Apoptosis of Human Pancreatic Cancer Cells.

Evidence-based complementary and alternative medicine : eCAM·2026
Same journal

RETRACTION: Thujone-Rich Fraction of <i>Thuja occidentalis</i> Demonstrates Major Anti-Cancer Potentials: Evidences from In Vitro Studies on A375 Cells.

Evidence-based complementary and alternative medicine : eCAM·2026
Same journal

RETRACTION: Application of <i>Antrodia camphorata</i> Promotes Rat's Wound Healing <i>In Vivo</i> and Facilitates Fibroblast Cell Proliferation <i>In Vitro</i>.

Evidence-based complementary and alternative medicine : eCAM·2026
Same journal

RETRACTION: Catechins and Sialic Acid Attenuate <i>Helicobacter pylori</i>-Triggered Epithelial Caspase-1 Activity and Eradicate <i>Helicobacter pylori</i> Infection.

Evidence-based complementary and alternative medicine : eCAM·2026
See all related articles

Related Experiment Video

Updated: May 17, 2026

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

Guidelines for developing yoga interventions for randomized trials.

Karen J Sherman1

  • 1Group Health Research Institute, Group Health Cooperative, 1730 Minor Avenue, Suite 1600, Seattle, WA 98101, USA ; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.

Evidence-Based Complementary and Alternative Medicine : Ecam
|October 20, 2012
PubMed
Summary
This summary is machine-generated.

Developing yoga protocols for health research requires careful consideration of intervention style, components, dosage, and instructor fidelity. This systematic approach guides researchers in creating effective and replicable yoga interventions for various health conditions.

Related Experiment Videos

Last Updated: May 17, 2026

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
07:56

Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS

Published on: June 24, 2025

Area of Science:

  • Mind-Body Interventions
  • Integrative Health Research
  • Yoga Therapy Protocol Development

Background:

  • Yoga, a complex mind-body discipline, lacks standardized protocols for health research.
  • Existing research on yoga for health concerns faces challenges due to the multifactorial nature of the practice.
  • Researchers require structured guidance for developing appropriate and explicit yoga interventions.

Purpose of the Study:

  • To propose a systematic approach for developing yoga treatment protocols in health research.
  • To assist researchers in selecting appropriate yoga interventions tailored to specific health conditions.
  • To provide a framework for creating explicit and replicable yoga protocols.

Main Methods:

  • Discussion of key domains for yoga protocol development.
  • Consideration of yoga style, intervention components (breathing, postures), and specific protocols.
  • Analysis of dosage parameters (frequency, duration) and instructor/fidelity monitoring.

Main Results:

  • A systematic framework is presented for yoga protocol design.
  • Identifies critical decision points including yoga style, components, dosage, and fidelity.
  • Highlights the need for explicit protocol development in yoga health research.

Conclusions:

  • A structured approach is essential for creating rigorous yoga interventions in health research.
  • Researchers must carefully define yoga style, components, dosage, and ensure instructor fidelity.
  • Further research is recommended to refine yoga protocol development methodologies.