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Updated: Aug 10, 2026

Murine Drinking Models in the Development of Pharmacotherapies for Alcoholism: Drinking in the Dark and Two-bottle Choice
Published on: January 7, 2019
Alcoholism and smoking
1Department of Family Medicine, University of Massachusetts Medical School, Fitchburg 01420.
Alcoholics are significantly more likely to smoke and struggle with quitting tobacco. This suggests a shared susceptibility to addiction, impacting public health.
Area of Science:
- Addiction research
- Behavioral science
- Public health
Background:
- Cigarette smoking and alcoholism are closely linked behaviors.
- Understanding the natural history of smoking in alcoholics is crucial for public health interventions.
Purpose of the Study:
- To compare the natural history of cigarette smoking in alcoholic and nonalcoholic populations.
- To investigate potential reasons for the strong association between alcoholism and smoking.
Main Methods:
- A case-control study design was employed.
- The study compared smoking behaviors and cessation success rates between alcoholic and nonalcoholic individuals.
Main Results:
- Eighty-three percent of alcoholics were smokers, versus 34% of nonalcoholics.
- Children who later became alcoholic were more likely to use tobacco regularly after trying it.
- Only 7% of alcoholic smokers successfully quit, compared to 49% of nonalcoholic smokers.
Conclusions:
- Alcoholism and smoking share common risk factors, potentially including a general susceptibility to addictive drugs.
- Tobacco smoking cessation is significantly less successful in individuals with alcoholism.
- Further research into smoking cessation strategies for alcoholics is warranted.
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