Related Experiment Video

Updated: May 17, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
05:45

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

Colon perforation caused by a foreign body in Hirschsprung disease

Sevgi Buyukbese Sarsu1, Süleyman Cüneyt Karakuş, Ali Uysal Erdem

  • 1Department of Pediatric Surgery, Gaziantep Children Hospital, Sehitkamil, Gaziantep, Turkey.

Journal of Pediatric Surgery
|October 23, 2012
PubMed

Insights

Accidental ingestion of radio-opaque foreign bodies in children is common. This case reveals Hirschsprung disease linked to a perforated sigmoid colon, suggesting congenital anomalies in differential diagnoses.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Medical Imaging

Background:

  • Foreign body ingestion is a frequent pediatric emergency, usually resolving without complications.
  • Most ingested foreign bodies pass through the gastrointestinal tract spontaneously.
  • Hirschsprung disease is a congenital condition affecting the large intestine's nerve supply.

Observation:

  • A case report details a pediatric patient with an impacted radio-opaque foreign body.
  • The foreign body was found lodged at the site of a perforated sigmoid colon.
  • This presentation is unique, being the first reported association of Hirschsprung disease with a foreign body perforation.

Findings:

  • The study presents a rare association between a radio-opaque foreign body and Hirschsprung disease.
  • A perforated sigmoid colon was identified as the location of the lodged foreign body.
  • This finding challenges the typical spontaneous passage of ingested foreign bodies in certain pediatric cases.

Implications:

  • Highlights the importance of considering congenital anomalies in pediatric cases of impacted foreign bodies.
  • Suggests Hirschsprung disease should be included in the differential diagnosis for obstructive symptoms with foreign bodies.
  • Emphasizes the need for thorough investigation in pediatric foreign body ingestions, especially with radio-opaque objects.

More Related Videos

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children04:55

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

Published on: September 11, 2018

A Mouse Model of Intestinal Partial Obstruction07:33

A Mouse Model of Intestinal Partial Obstruction

Published on: March 5, 2018

Related Concept Videos

Esophageal Perforation-I: Introduction01:22

Esophageal Perforation-I: Introduction

Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Diverticular Disease of the Colon01:27

Diverticular Disease of the Colon

Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD: