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Updated: May 17, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice
Published on: August 2, 2017
Nocturnal evolution of heart rate variability indices in sleep apnea
María J Lado1, Arturo J Méndez, Leandro Rodríguez-Liñares
1Department of Computer Science, ESEI, University of Vigo, Ourense, Spain. mrpepa@uvigo.es
Abstract:
Heart rate variability (HRV) is a valuable clinical tool in diagnosing multiple diseases. This paper presents the results of a spectral HRV analysis conducted with 46 patients. HRV indices for the whole night show differences among patients with severe and mild apnea, and healthy subjects. These differences also appear when performing the analysis over 5-min intervals, regarding apneas being present or not in the intervals. Differences were also observed when analyzing the HRV nocturnal evolution. Results are consistent with the hypothesis that cardiovascular risk remains constant for OSA patients while it increases towards the end of the night for healthy subjects.
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