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Generation of Lymph Node-fat Pad Chimeras for the Study of Lymph Node Stromal Cell Origin
Published on: December 16, 2013
Caught in the act: reprogramming of adipocytes into lymph-node stroma
1Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany. boehm@immunbio.mpg.de
Immunity
|October 23, 2012
Abstract:
Interactions between stromal organizer cells and hematopoietic lymphoid inducer cells initiate lymph-node formation. In this issue of Immunity, Bénézech et al. demonstrate that adipocyte precursors give rise to lymph-node stromal organizer cells, illuminating an important step in lymphoid-tissue development.
