Related Experiment Video
Updated: May 17, 2026

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
Published on: September 19, 2025
Outcome of long-term mechanical ventilation support in children
Shao-Hsuan Hsia1, Jainn-Jim Lin, I-Anne Huang
1Division of Pediatric Critical Care and Emergency Medicine, Taiwan, ROC. shsia@adm.cgmh.org.tw
Insights
Taiwan has seen an increase in children requiring long-term mechanical ventilation (MV) support, primarily due to neurological conditions. Most of these children are now cared for in respiratory care wards.
Area of Science:
- Pediatric critical care
- Respiratory medicine
- Neurology
Background:
- Advances in technology and care have improved outcomes for patients on long-term mechanical ventilation (MV).
- This study investigates the current status of pediatric patients requiring long-term MV in Taiwan.
Purpose of the Study:
- To examine the clinical characteristics and outcomes of children on long-term mechanical ventilation in Taiwan.
- To identify the primary causes and management trends for pediatric patients requiring prolonged MV support.
Main Methods:
- Retrospective review of medical records for patients aged 3 months to 18 years.
- Data collected between January 1998 and December 2006.
- Systematic review of clinical factors and patient outcomes.
Main Results:
- 139 children (38.1% girls, 61.9% boys) were included.
- Neurologic/neuromuscular diseases (71.9%) were the most common underlying conditions, followed by airway/lung dysfunction (13.7%).
- Common reasons for re-hospitalization included infection (47.7%) and elective procedures (13.9%).
- Outcomes included death (26.6%), transfer to respiratory care wards (58.3%), and home care (15.1%).
Conclusions:
- There is an increasing population of children requiring long-term MV in Taiwan.
- The predominant cause of respiratory insufficiency has shifted to neurogenic causes.
- The majority of these children are managed in local hospital respiratory care wards.
Background:
Improved technology and care in recent years have significantly improved the prognosis and quality of life for patients on long-term mechanical ventilation. This study examined the status of children on long-term mechanical ventilation (MV) support in Taiwan.
Methods:
The medical records of patients between January 1998 and December 2006 were retrospectively reviewed, and the clinical factors were systematically reviewed.
Results:
One hundred and thirty-nine (139) patients aged 3 months to 18 years, with 53 (38.1%) girls and 86 (61.9%) boys, were enrolled. The common underlying disorders included neurologic/neuromuscular diseases (n=100, 71.9%) and airway/lung dysfunction (n=19, 13.7%). After instituting MV, the children returned to the medical center mainly for infection (n=157, 47.7%) and elective surgery or procedures (n=46, 13.9%). After long-term follow-up, 37 (26.6%) died, 81 (58.3%) were transferred to respiratory care wards in local hospitals, and 21 (15.1%) received home care support.
Conclusions:
There are now more children on long-term MV support in Taiwan and most are in respiratory care wards in local hospitals. The shift in underlying diagnoses from pulmonary disease to neurogenic respiratory insufficiency affects hospitalization. The main cause of respiratory insufficiency is neurologic insult.
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Acute Respiratory Failure-V
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Pulmonary Cycle: Exhalation