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Fusarium peritonitis in peritoneal dialysis: report of two cases
V Chiaradia1, D Schinella, L Pascoli
1Laboratory of Microbiology and Immunology, General Hospital, Pordenone, Italy.
Microbiologica
|January 1, 1990
Abstract:
This report describes two cases of peritoneal dialysis-related peritonitis caused by Fusarium species which have been incriminated in a variety of disease conditions. Treatment with 5-Fluorocytosine was unsuccessful, but removal of the catheter resulted in a rapid resolution of the infections.
Insights
Fusarium species caused two cases of peritonitis in patients undergoing peritoneal dialysis. Catheter removal rapidly resolved these fungal infections, while antifungal treatment failed.
Area of Science:
- Mycology
- Infectious Diseases
- Nephrology
Background:
- Peritonitis is a serious complication of peritoneal dialysis.
- Fungal peritonitis, particularly from Fusarium species, poses a treatment challenge.
Observation:
- Two patients undergoing peritoneal dialysis developed peritonitis.
- The causative agent was identified as Fusarium species.
Findings:
- Standard antifungal treatment with 5-Fluorocytosine was ineffective.
- Surgical removal of the peritoneal dialysis catheter led to rapid and complete resolution of the infection.
Implications:
- Catheter removal is a critical intervention for Fusarium peritonitis in peritoneal dialysis patients.
- This highlights the importance of considering fungal etiologies in refractory peritonitis.
- Further research into optimal treatment strategies for fungal peritonitis is warranted.