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Reverse Genetics Mediated Recovery of Infectious Murine Norovirus
Published on: June 24, 2012
Complete genome sequences of novel rat noroviruses in Hong Kong
Herman Tse1, Wan-Mui Chan, Carol S F Lam
1Department of Microbiology, The University of Hong Kong, Hong Kong SAR, China.
Abstract:
We report two genome sequences of novel noroviruses isolated from fecal swab specimens of brown rats in Hong Kong. The complete genome is approximately 7.5 kb in length and consists of 3 overlapping open reading frames encoding ORF1 polyprotein, VP1, and VP2, respectively. Sequence analysis suggested that these noroviruses should be classified in genogroup V, but they are distinct from other known rodent noroviruses and represent a novel cluster within the genogroup.
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