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Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Relationship of venous blood gas with cervical esophagogastric anastomotic leak
Gholamraza Mohajeri1, Abas Tabatabaei, Mozafar Hashemi
1Department of Thoracic Surgery, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Objective:
this study investigated the relationship between various parameters of venous blood gas analysis of gastric fundus veins and cervical esophagogastric anastomotic leaks after transhiatal esophagectomy.
Background:
decreased tissue perfusion is one of the causes of anastomotic leak. There are various methods used to assess gastric conduit perfusion, with different results, and we lack a reliable method.
Method:
this descriptive study, performed from March 2008 to October 2010, consisted of 45 patients with esophageal cancer who underwent transhiatal esophagectomy. After gastrolysis, blood samples were taken from a gastric fundus vein and submitted for venous blood gas analysis. The cervical wounds were examined 5 days postoperatively. The patients were divided into 2 groups based on the presence of leakage, and mean values of the venous blood gas analysis were compared.
Results:
we observed significant differences in mean pH, PCO(2), and O(2) saturation between the 2 groups (p = 0.04, p = 0.03, and p = 0.04, respectively).
Conclusion:
venous blood gas analysis of gastric fundus veins appears to be a feasible and fast method for intraoperative assessment of microperfusion in the gastric fundus.
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