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Ocular convergence deficits in schizophrenia.

Mark S Bolding1, Adrienne C Lahti, Timothy J Gawne

  • 1Department of Vision Sciences, University of Alabama at Birmingham Birmingham, AL, USA.

Frontiers in Psychiatry
|October 23, 2012
PubMed
Summary

Individuals with schizophrenia (SZ) show more symptoms of convergence insufficiency (CI) but not necessarily clinical signs. The Convergence Insufficiency Symptom Survey (CISS) may not accurately identify CI in SZ patients.

Keywords:
convergence insufficiencyendophenotypeeye movement dysfunctionoculomotorschizophreniavergence

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Psychiatry

Background:

  • Individuals with schizophrenia (SZ) may have a higher prevalence of convergence insufficiency (CI).
  • Existing research suggests a potential link between SZ and CI, necessitating further investigation.
  • Understanding this relationship can inform diagnostic and therapeutic strategies.

Purpose of the Study:

  • To investigate the prevalence of clinical signs of CI in individuals with SZ.
  • To evaluate the effectiveness of the Convergence Insufficiency Symptom Survey (CISS) for identifying CI in this population.
  • To explore the correlation between subjective CI symptoms and objective clinical measures in SZ.

Main Methods:

  • A comparative study involving 20 participants with SZ and 20 healthy controls (HC).
  • Assessment of clinical signs of CI and administration of the CISS.
  • Measurement of fusional reserve using Sheard's criteria.

Main Results:

  • The prevalence of CI in the SZ group was 15%, not significantly different from norms.
  • SZ participants reported significantly higher CISS scores than HC.
  • CISS scores did not correlate with clinical CI measures in SZ, except for reduced fusional reserve.

Conclusions:

  • While individuals with SZ report CI symptoms, clinical measures do not consistently support a CI diagnosis.
  • The CISS may not be a reliable tool for detecting CI in individuals with SZ.
  • Further research is required to understand the discrepancy between reported symptoms and clinical findings in SZ patients regarding CI.